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1.
Appl. cancer res ; 32(4): 111-115, 2012. ilus, tab
Article in English | LILACS, Inca | ID: lil-706009

ABSTRACT

Objective: Developing countries have a high incidence of head and neck squamous cell carcinoma (HNSCC). Risk factors are smoking and alcohol consumption; socioeconomic status and oral health may be associated with etiology. The aim of this study was to evaluate the sociodemographicprofile and oral health of patients with primary HNSCC, as well as the clinical and histopathological characteristics of the tumor. Material and Methods: We evaluated 78 patients; data about sex, age, skin color, schooling, oral hygiene, smoking, alcohol consumption and socioeconomic status were collected using a structured questionnaire. An intraoral examination provided dataabout caries, missing teeth and dental prosthesis. Hospital records were reviewed to collect clinical tumor information. Results: Mean age was 57.6 years; most participants were male,white, former or current smokers and moderate or high consumption of alcoholic beverages with low socioeconomic and educational levels. The majority of patients were disease-free at 2 year-follow up. Classification showed 60.2% of the tumors as T1 and T2 and 59% had no regional involvement. Most tumors were found in the mouth, and the tongue was the most frequent site. Histopathological examination revealed that 57.7% of the tumors were classified as moderateand poor prognosis. Conclusion: The profile of patients with HNSCC was similar to that found in other populations, but there is a decline in clinical stage at the time of diagnosis, and detecting this tumor at an early stage can be an effective mean to determine a better prognosis for patients


Subject(s)
Humans , Carcinoma, Squamous Cell , Head and Neck Neoplasms/diagnosis , Head and Neck Neoplasms/epidemiology , Head and Neck Neoplasms/etiology
2.
Rev. bras. cir. plást ; 26(3): 385-389, July-Sept. 2011. ilus
Article in English | LILACS | ID: lil-608193

ABSTRACT

INTRODUCTION: In the present study, the stability and biocompatibility of a 30 percent polymethylmethacrylate (PMMA) filling material implanted in the masseter muscle of rats were investigated according to the cytologic characteristics presented in the graft versus host reaction. METHODS: The study included 20 rats, which were divided into 4 groups: groups I, II, III, and IV corresponded to animals evaluated 7, 14, 45, and 60 days after surgery, respectively. The implant was placed in the right masseter muscle at the level of the mandibular angle. RESULTS: After 7 days, lymphoplasmacytic inflammatory infiltrates, a fibrous capsule, a large number of neutrophils, macrophages, and exudate were observed. The second group (14 days) showed granulation tissue composed of a lymphoplasmacytic inflammatory infiltrate, newly formed vessels, and a fibrous capsule. However, the second group also exhibited regeneration of the muscle fibers, and a decreased number of neutrophils and exudate. After 45 and 60 days, the inflammatory infiltrate decreased in intensity compared to the first 2 groups. CONCLUSIONS: The inflammatory reaction caused by PMMA is transient and does not compromise the function and the shape of the masseter muscle tissue, suggesting that PMMA is biocompatible.


INTRODUÇÃO: Este trabalho busca avaliar, em ratos, a estabilidade e a biocompatibilidade de um material de preenchimento à base de polimetilmetacrilato (PMMA) a 30 por cento implantado no músculo masseter, por meio do padrão, e a organização reacional no tecido receptor. MÉTODO: Foram utilizados 20 ratos, divididos em quatro grupos: grupo I, que correspondeu ao período de 7 dias de pós-operatório; grupo II, de 14 dias; grupo III, de 45 dias; e grupo IV, de 60 dias. O implante foi realizado no músculo masseter direito, na região do ângulo da mandíbula. RESULTADOS: No período de 7 dias, observou-se presença de infiltrado inflamatório linfoplasmocitário, com formação de cápsula fibrosa e presença de grande número de neutrófilos, macrófagos e formação de exsudatos. Em 14 dias, observou-se a formação de um tecido de granulação composto por infiltrado inflamatório linfoplasmocitário, vasos de neoformação e cápsula fibrosa. Porém, nesse tempo experimental, nota-se a regeneração das fibras musculares e a diminuição do número de neutrófilos e exsudatos. Após 45 dias e 60 dias, observou-se, no tecido muscular, diminuição da intensidade do infiltrado inflamatório, comparativamente aos tempos experimentais anteriores. CONCLUSÕES: A reação inflamatória provocada pelo PMMA é transitória e não compromete as funções e o contorno desse tecido muscular, o que sugere que o PMMA é biocompatível.


Subject(s)
Animals , Rats , History, 21st Century , Rats , Biocompatible Materials , Dental Implants , Muscle Fibers, Skeletal , Polymethyl Methacrylate , Inflammation , Mandible , Masseter Muscle , Neutrophils , Rats/anatomy & histology , Rats/immunology , Biocompatible Materials/analysis , Biocompatible Materials/adverse effects , Dental Implants/adverse effects , Dental Implants/veterinary , Muscle Fibers, Skeletal/pathology , Polymethyl Methacrylate/analysis , Polymethyl Methacrylate/therapeutic use , Inflammation/veterinary , Mandible/immunology , Masseter Muscle/anatomy & histology , Masseter Muscle/immunology , Neutrophils/pathology
4.
Rev. Fac. Odontol. Porto Alegre ; 46(1): 32-36, jul. 2005. graf
Article in Portuguese | LILACS, BBO | ID: lil-436350

ABSTRACT

Com o objetivo de obter um perfil de indivíduos afetados por ameloblastoma e comparar os resultados com os estudos encontrados na literatura, realizou-se uma análise retrospectiva dos casos de ameloblastomas do Laboratório de Patologia Bucal da FO-UFRGS. Os resultados revelaram uma maior ocorrência em indivíduos jovens, do sexo feminino, raça branca, localização predominantemente na mandíbula e tipo histológico plexiforme. Conclui-se que, o perfil dos pacientes com ameloblastoma diagnosticados no Laboratório de Patologia Bucal da FO-UFRGS concorda com o perfil de pacientes com ameloblastoma diagnosticado em outras partes do mundo e relatado na literatura diferindo apenas no que se refere a faixa etária no momento do diagnóstico


Subject(s)
Humans , Male , Female , Ameloblastoma/epidemiology , Jaw Neoplasms/epidemiology , Age Factors , Ethnic Distribution , Sex Factors
5.
Rev. Fac. Odontol. Porto Alegre ; 42(1): 31-33, jul. 2001. ilus, tab
Article in Portuguese | LILACS, BBO | ID: lil-329109

ABSTRACT

Imagens radiolúcidas e ou radiopacas sob restauraçöes de amálgama que resultam em interpretaçöes dúbias podem levar a uma incorreta decisäo terapêutica. Imagens radiolúcidas podem representar dentina desmineralizada, lesöes ativas de cárie ou materiais näo radiopacos. Imagens radiopacas, freqüentemente interpretadas como dentina reacional, podem também representar dentina desmineralizada. Para avaliar essas imagens, foram obtidas radiografias interproximais de 53 dentes posteriores extraídos que apresentavam restauraçäo em amálgama, posteriormente seccionados para análise visual. Destes, 15 (28,3 por cento) apresentaram imagens radiolúcidas e ou radiopacas sob a restauraçäo, na maioria dos casos (11) na forma combinada e todas as áreas radiolúcidas e ou radiopacas observadas corresponderam, nas secçöes dos dentes, à imagem característica de dentina desmineralizada


Subject(s)
Dental Caries , In Vitro Techniques , Radiography, Dental
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